Natural Gain Plus Because it involves your metabolism, your results will be unique to you, whether or not it's a faster or slower Natural Gain Plus. Or you may discover you had more energy on those days you ate no carbs at all. Keep a record of your macros, your exercise, and your moods alongside your Natural Gain Plus progress. Polycystic ovary syndrome: Natural Gain Plus can lower insulin levels, which may play a role in treating polycystic ovary syndrome. Epilepsy: Research has indicated that the Natural Gain Plus diet can cause a sizeable reduction in the number of seizures experienced by epileptic children. This forces the body to burn energy from fat.